Polyclonal Antibody to TYK2 (Phospho-Tyr1054)
Produktgrößen
50 µl
£511,00
35-1142-50UL
100 µl
£581,00
35-1142-100UL
Über dieses Produkt
- SKU:
- 35-1142
- Zusätzliche Namen:
- tyrosine kinase 2|| JTK1
- Klonalität:
- Polyclonal
- Weitere Details:
- TYK2 encodes a member of the tyrosine kinase and; more specifically; the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such; it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Zheng H; et al. (2005) Mol Cell Proteomics. 4(6):721-730. Gauzzi MC; et al. (1996) J Biol Chem. 271(34): 20494-20500.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 1054 (H-E-Y(p)-Y-R) derived from Human TYK2.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg