Recombinant Human NGAL/Lipocalin-2/LCN2 (C-6His; Human Cells)
Produktgrößen
10 µg
£549,00
32-9740-10UG
50 µg
£706,00
32-9740-50UG
Über dieses Produkt
- SKU:
- 32-9740
- Zusätzliche Namen:
- Neutrophil gelatinase-associated lipocalin; NGAL; 25 kDa alpha-2-microglobulin-relatedsubunit of MMP-9; Lipocalin-2; Oncogene 24p3; Siderocalin LCN2;p25;HNL;NGAL
- Weitere Details:
- Source : Human Cells;LCN2 is iron-trafficking protein involved in multiple processes such as apoptosis; innate immunity and renal development. LCN2 binds iron through association with 2;5-dihydroxybenzoic acid (2;5-DHBA); a siderophore that shares structural similarities with bacterial enterobactin; and delivers or removes iron from the cell; depending on the context. LCN2 is involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis; while iron-free form decreases intracellular iron levels; inducing expression of the proapoptotic protein BCL2L11/BIM; resulting in apoptosis. LCN2 is involved in innate immunity; possibly by sequestrating iron; leading to limit bacterial growth.
- Versandbedingungen:
- Dry Ice
- Hersteller:
- Abeomics
- Typ:
- Cells
- Datenblatt des Herstellers:download_pdf.php