Recombinant Mouse Interleukin-13/IL-13 (Ser26-Phe131;C-6His)
Produktgrößen
50 µg
£847,00
32-9703-50UG
500 µg
£2330,00
32-9703-500UG
Über dieses Produkt
- SKU:
- 32-9703
- Zusätzliche Namen:
- Interleukin-13; IL-13; T-Cell Activation Protein P600; Il13; Il-13
- Weitere Details:
- Source : Human Cells;Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2; IL4R) and activates STAT-6. IL13 initially binds IL-13R-Alpha1 with low affinity and triggers association of IL4R-Alpha; generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13R-Alpha2 with high affinity; which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php