Recombinant Human OX-2/MOX1/CD200 (C-Fc)
Produktgrößen
50 µg
£656,00
32-9686-50UG
500 µg
£1959,00
32-9686-500UG
Über dieses Produkt
- SKU:
- 32-9686
- Zusätzliche Namen:
- OX-2 Membrane Glycoprotein; CD200; MOX1; MOX2
- Weitere Details:
- Source : Human Cells;CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells; basophils; macrophages; and dendritic cells; which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells; CD200R initiates inhibitory signals following receptor-ligand contact. In T cells; CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition; CD200 also plays an important role in prevention of graft rejection; autoimmune diseases and spontaneous abortion.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php