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Proteine und Peptide

Recombinant Human B7-1/CD80 (C-mFC)

Produktgrößen
50 µg
£584,00
32-9640-50UG
500 µg
£1615,00
32-9640-500UG
Über dieses Produkt
SKU:
32-9640
Zusätzliche Namen:
CD80; Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80
Weitere Details:
Source : Human Cells;Cluster of Differentiation 80; also called B7-1; is a member of cell surface immunoglobulin superfamily which plays key; yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells.
Versandbedingungen:
Ambient
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins