Recombinant Human Interleukin-17 receptor A/IL-17RA/CD217(C-6His)
Produktgrößen
50 µg
£554,00
32-9629-50UG
500 µg
£1039,00
32-9629-500UG
Über dieses Produkt
- SKU:
- 32-9629
- Zusätzliche Namen:
- IL17Rinterleukin-17 receptor A; interleukin 17 receptor A; IL17RA;CD217
- Weitere Details:
- Source : Human Cells;CD217; also known as Interleukin-17 receptor A; is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F; it binds to IL17A with higher affinity than to IL17F and binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. It also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. The activation of IL17RA would lead to induction of expression of inflammatory chemokines and cytokines such as CXCL1; CXCL8/IL8 and IL6. The signaling events of IL 17 includes activation of NF kappa B and JNK; and require TNF receptor associated factors 6 (TRAF6) in the signaling pathway.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php