Recombinant Human Tyrosine-protein kinase receptor ROR1/ROR1(C-Fc)
Produktgrößen
50 µg
£554,00
32-9628-50UG
500 µg
£1039,00
32-9628-500UG
Über dieses Produkt
- SKU:
- 32-9628
- Zusätzliche Namen:
- neurotrophic tyrosine kinase receptor-related 1; receptor tyrosine kinase-like orphan receptor 1; ROR1;tyrosine-protein kinase transmembrane receptor ROR1
- Weitere Details:
- Source : Human Cells;ROR1; also known as Neurotrophic tyrosine kinase; receptor-related 1; belongs to the ROR subfamily of Tyr protein kinase family;a protein kinase superfamily. It has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence; a 377 aa extracellular domain (ECD); a 21 aa transmembrane segment; and a 510 aa cytoplasmic region. Human ROR1 shares 97% and 58% aa sequence identity with mouse ROR1 and human ROR2; respectively. ROR1 may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. ROR1 expressed strongly in human heart; lung and kidney; but weakly in the CNS. Its Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers; including those originating from CNS or PNS neuroectoderm.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php