Recombinant Human Troponin C/TN-C/TNNC1(N-6His)
Produktgrößen
50 µg
£706,00
32-9550-50UG
500 µg
£1726,00
32-9550-500UG
Über dieses Produkt
- SKU:
- 32-9550
- Zusätzliche Namen:
- CMH7; TNNC1; TNNI3; Troponin I
- Weitere Details:
- Source : E. coli;Troponin I; also known as TNI; is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase; Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle; while TNNI1 and TNNI2 (encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with heriditary cardiomyopathy. Human cardiac Troponin I shares 93% amino acid sequence identity with mouse and rat cardiac Troponin I.
- Versandbedingungen:
- Dry Ice
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php