Recombinant Human Stimulator of Interferon Genes Protein/Sting (N-Sumo-6His)
Produktgrößen
50 µg
£772,00
32-9542-50UG
500 µg
£2009,00
32-9542-500UG
Über dieses Produkt
- SKU:
- 32-9542
- Zusätzliche Namen:
- Stimulator of interferon genes protein;TMEM173;Mediator of IRF3 activation;sting;
- Weitere Details:
- Source : E. coli;Stimulator of Interferon Gene(Sting;TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20); four transmembrane segments (aa 21-173); and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells; alveolar type 2 pneumocytes; bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I; MAVS and SSR2; RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
- Versandbedingungen:
- Dry Ice
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php