Recombinant Cynomolgus BCMA (C-Fc)
Produktgrößen
50 µg
£722,00
32-9518-50UG
500 µg
£1959,00
32-9518-500UG
Über dieses Produkt
- SKU:
- 32-9518
- Zusätzliche Namen:
- Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma
- Weitere Details:
- Source : Human Cells;B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF; it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF; members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface; BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development;function and regulation.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php