Recombinant Human OX40/TNFRSF4/CD134 (C-Fc)
Produktgrößen
50 µg
£691,00
32-9500-50UG
500 µg
£1959,00
32-9500-500UG
Über dieses Produkt
- SKU:
- 32-9500
- Zusätzliche Namen:
- Tumor necrosis factor receptor superfamily member 4;TNFRSF4;OX40;CD134;Txgp1; REF: C1130
- Weitere Details:
- Source : Human Cells;OX40; also termed CD134 and TNFRSF4; is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions; including cytokine production; expansion; and survival; are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance; peripheral T-cell homeostasis; and T-cell-mediated inflammatory diseases.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php