Recombinant Mouse Interleukin-23/IL-23 (C-6His)
Produktgrößen
50 µg
£948,00
32-9457-50UG
500 µg
£2879,00
32-9457-500UG
Über dieses Produkt
- SKU:
- 32-9457
- Zusätzliche Namen:
- SGRF;IL-23p19;CLMF p40;IL-12 subunit p40;NKSF2
- Weitere Details:
- Source : Human Cells;Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits; a p19 subunit that is unique to IL-23; and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12; as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages; dendritic cells; T cells; and endothelial cells; only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to; but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells; the effects of IL-23 is restricted to memory T cells.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php