Recombinant Mouse Matrix Metalloproteinase-9/MMP-9
Produktgrößen
50 µg
£897,00
32-9393-50UG
500 µg
£2009,00
32-9393-500UG
Über dieses Produkt
- SKU:
- 32-9393
- Zusätzliche Namen:
- Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
- Weitere Details:
- Source : Human Cells;Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin; collagen types IV and V; elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes; monocytes; macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally; MMP-9 may be divided into five distinct domains: a prodomain which is cleaved upon activation; a gelatinbinding domain consisting of three contiguous fibronectin type II units; a catalytic domain containing the zinc binding site; a prolinerich linker region; and a carboxyl terminal hemopexinlike domain.
- Versandbedingungen:
- Dry Ice
- Hersteller:
- Abeomics
- Typ:
- Assay Kits:MMP
- Datenblatt des Herstellers:download_pdf.php