Recombinant Human Serine Protease HTRA2/HTRA2/Omi (C-6His)
Produktgrößen
50 µg
£558,00
32-9308-50UG
500 µg
£1110,00
32-9308-500UG
Über dieses Produkt
- SKU:
- 32-9308
- Zusätzliche Namen:
- Serine protease HTRA2; mitochondrial;High temperature requirement protein A2;HtrA2;Omi stress-regulated endoprotease;Serine protease 25;Serine proteinase OMI;HTRA2;OMI; PRSS25
- Weitere Details:
- Source : Human Cells;High temperature requirement protein A2(HTRA2) is a single-pass membrane protein .It contains 1 PDZ (DHR) domain and belongs to the peptidase S1C family. HtrA2 can be released from the mitochondria during apoptosis and uses its four most N-terminal amino acids to mimic a caspase and be recruited by IAP caspase inhibitors such as XIAP and CIAP1/2. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins; IAPs); leading to an increase in caspase activity; or by a BIRC inhibition-independent; caspase-independent and serine protease activity-dependent mechanism. The protein cleaves THAP5 and promotes its degradation during apoptosis.
- Versandbedingungen:
- Dry Ice
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php