Recombinant Human BTN3A1/CD277 (C-hFc)
Produktgrößen
50 µg
£584,00
32-9193-50UG
500 µg
£1676,00
32-9193-500UG
Über dieses Produkt
- SKU:
- 32-9193
- Zusätzliche Namen:
- Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5
- Weitere Details:
- Source : Human 293 Cells;BTN3A1; also known as CD277; is a type I transmembrane glycoprotein that belongs to the Ig superfamily. BTN3A1 is expressed on various immune cells. Similar to BTN3A2 and BTN3A3; BTN3A1 is composed of an extracellular N-terminal IgV and a membrane-proximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family co-stimulatory molecules; suggesting structural and functional similarities between the two protein families. BTN3A1 is essential for the activation of Vgamma9Vdelta2 T cells following the detection of distressed cells. The anti-tumor responses of Vgamma9Vdelta2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php