Recombinant Cynomolgus B7-1/CD80 (C-His)
Produktgrößen
50 µg
£493,00
32-9187-50UG
500 µg
£1009,00
32-9187-500UG
Über dieses Produkt
- SKU:
- 32-9187
- Zusätzliche Namen:
- T-lymphocyte activation antigen CD80; Activation B7-1 antigen; B7; CD80
- Weitere Details:
- Source : Human 293 Cells;CD80; also known as B7-1; is a member of cell surface immunoglobulin superfamily. CD80 is predominately expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells. CD80 and CD86; together with their receptors CD28 and CTLA4; form one of the dominant co-stimulatory pathways that mediate T- and B- cell responses. Although both CD28 and CTLA4 can bind to CD80 and CD86; CTLA-4 has 20-100 fold higher affinity than CD28 plays a role in the down-regulation of the immune response. CD80 is also involved in the induction of innate immune responses by activating NF-kB-signaling pathway in macrophages. Therefore; CD80 has the potential to be promising therapeutic targets for autoimmune diseases and various carcinomas.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php