Recombinant Human Complement Factor H-related Protein 1/CFHR1(C-His)
Produktgrößen
50 µg
£722,00
32-9176-50UG
500 µg
£1959,00
32-9176-500UG
Über dieses Produkt
- SKU:
- 32-9176
- Zusätzliche Namen:
- Complement Factor H-Related Protein 1; FHR-1; H Factor-Like Protein 1; H-Factor-Like 1; H36;CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2
- Weitere Details:
- Source : Human 293 Cells;Complement factor H-related protein 1 (CFHR1) is a secreted protein that is a member of the complement factor H protein family. CFHR1 is expressed by hepatocytes and exists as two differentially glycosylated isoforms. The human complement factor H protein family consists of the complement and immune regulators factor H; the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains; termed short consensus repeats (SCRs) or complement control modules. CFHR1 binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen; which is proteolytically activated. CFHR1 might mediate complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. A common CFHR1/CFHR3 genetic deletion has been recognized as being protective against age-related macular degeneration and nephropathy.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php