Recombinant Cynomolgus OX40L/TNFSF4 (N-His)
Produktgrößen
50 µg
£618,00
32-9167-50UG
500 µg
£2154,00
32-9167-500UG
Über dieses Produkt
- SKU:
- 32-9167
- Zusätzliche Namen:
- Tumor necrosis factor ligand 2B; TNFSF4; OX-40L
- Weitere Details:
- Source : Human 293 Cells;OX40L; also known as CD252 is a type II transmembrane glycoprotein that is a member of the tumor necrosis factor (TNF) ligand family. OX40L is expressed on the surface of activated B cells; T cells; dendritic cells; and endothelial cells. It is an essential co-stimulatory molecule that plays an important role in the regulation of T-cell-mediated immunity. OX40L might play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD4-stimulated B cells; this cytokine along with CD7 has been shown to provide CD28-independent costimulatory signals to T cells. The interaction of OX40 and OX40L on activated T cells in situ in tumors has been found to facilitate immune responses and subsequent tumor regression.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php