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Proteine und Peptide

Biotinylated Recombinant Human IL-2RA/CD25 (C-Avi&His)

Produktgrößen
25 µg
£772,00
32-9153-25UG
250 µg
£1726,00
32-9153-250UG
Über dieses Produkt
SKU:
32-9153
Zusätzliche Namen:
Interleukin-2 receptor subunit alpha;CD25;p55;TAC antigen;IL2-RA;IL-2R subunit alpha;IL-2-RA;IL2RA;IL-2 receptor subunit alpha
Weitere Details:
Source : Human 293 Cells;Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane glycoprotein; contains 2 Sushi (CCP/SCR) domains. IL2RA is expressed on activated T cells and regulatory T cells; and can bind IL2 with low affinity by itself. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains; together with the common gamma chain (IL2RG); constitute the high-affinity IL2 receptor. While homodimeric alpha chains (IL2RA) result in low-affinity receptor; homodimeric beta (IL2RB) chains produce a medium-affinity receptor. CD25 has been previously regarded as an activation marker on dendritic cells. Although both murine and human dendritic cells can express CD25; they do not express the beta-chain of the IL-2 receptor; which is indispensable for the execution of IL-2 signaling.
Versandbedingungen:
Dry Ice
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins