Recombinant Human Fc gamma RIIB/CD32b (C-His)
Produktgrößen
50 µg
£625,00
32-9148-50UG
500 µg
£1959,00
32-9148-500UG
Über dieses Produkt
- SKU:
- 32-9148
- Zusätzliche Namen:
- Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; Fc-Gamma RII-b; Fc-Gamma-RIIb; FcRII-b; CD32; CD32b; FCGR2B; FCG2; IGFR2
- Weitere Details:
- Source : Human 293 Cells;Fc gamma RIIB; also known as CD32b is a low-affinity receptor that recognizes the Fc portion of IgG. CD32b is expressed on both myeloid cells and lymphoid lineages as well as non-hematopoietic origin cells. CD32b has an intrinsic cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM) and triggers an inhibitory signal upon ligand binding. Ligation of CD32B on B cells down-regulates antibody production and can facilitate apoptosis in certain conditions. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may be a potential target for monoclonal antibody therapy for malignancies.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php