Recombinant Mouse TREM-1 (C-His)
Produktgrößen
50 µg
£722,00
32-9147-50UG
500 µg
£1959,00
32-9147-500UG
Über dieses Produkt
- SKU:
- 32-9147
- Zusätzliche Namen:
- Triggering receptor expressed on myeloid cells 1; TREM-1; CD354; Trem1
- Weitere Details:
- Source : Human 293 Cells;Triggering Receptor Expressed on Myeloid Cells 1; known as TREM-1; is a transmembrane protein with a single Ig-like domain. TREM-1 is expressed on blood neutrophils and monocytes; and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. TREM-1 associates with the adapter protein; DAP12; to deliver an activating signal; which stimulates neutrophil and monocyte-mediated inflammatory responses. TREM-1 also triggers the release of pro-inflammatory chemokines and cytokines; as well as increased surface expression of cell activation markers. TREM-1 is an amplifier of inflammatory responses that are triggered by bacterial and fungal infections and are a crucial mediator of septic shock.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php