Recombinant Human IL-3R alpha/CD123(C-hFc)
Produktgrößen
50 µg
£722,00
32-9140-50UG
500 µg
£1959,00
32-9140-500UG
Über dieses Produkt
- SKU:
- 32-9140
- Zusätzliche Namen:
- Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha;IL-3RA; IL3RA;CD123
- Weitere Details:
- Source : Human 293 Cells;CD123; also known as Interleukin-3 receptor subunit alpha; is a glycoprotein that belongs to the type I cytokine receptor family. CD123 is a heterodimer with an alpha and a beta subunit. The alpha subunit alone binds IL-3 with low affinity. The beta subunit does not bind IL-3 by itself but is required for the high-affinity binding of IL-3 to the heterodimeric receptor complex. CD123 induces the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as a variety of lineage-committed cells. CD123 has been identified as a potential immunotherapeutic target due to its overexpression in AML compared with normal hematopoietic stem cells.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php