Recombinant Human Cadherin-1/E-cadherin/CDH1 (C-His)
Produktgrößen
50 µg
£554,00
32-9120-50UG
500 µg
£1534,00
32-9120-500UG
Über dieses Produkt
- SKU:
- 32-9120
- Zusätzliche Namen:
- Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324
- Weitere Details:
- Source : Human 293 Cells;E-Cadherin is a calcium-dependent cell adhesion glycoprotein that belongs to the cadherin family. E-Cadherin is expressed in non-neural epithelial tissues. It tends to interact with each other in a homophilic manner in connecting cells. E-Cadherin clusters are critical components of adherent junctions between epithelial cells and act in the formation and maintenance of the epithelial cell barrier. E-Cadherin is involved in mechanisms regulating cell-cell adhesions; mobility and proliferation of epithelial cells and has a potent invasive suppressor role. E-Cadherin loss contributes to cancer metastasis. The extracellular E-Cadherin N-terminal domain can be cleaved by several proteases and is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php