Recombinant Cyno NKG2A & CD94 Heterodimer
Produktgrößen
50 µg
£656,00
32-9072-50UG
500 µg
£1534,00
32-9072-500UG
Über dieses Produkt
- SKU:
- 32-9072
- Zusätzliche Namen:
- NKG2A&CD94
- Weitere Details:
- Source : Human 293 Cells;NKG2-A contains C-type lectin domain and belongs to the killer cell lectin-like receptor (KLR) family. KLR family is a group of transmembrane proteins preferentially expressed in natural killer (NK) cells. NK cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. CD94; also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1); is expressed on the surface of NK cells in the innate immune system. CD94 plays a role as a receptor for the recognition of MHC class I Human Leukocyte Antigen (HLA)-E molecules by NK cells and some cytotoxic T-cells. CD94 can form disulfide-bonded heterodimer with NKG2A on the surface of NK cells. The CD94/NKG2A complex interacts with HLA-E on target cells and inhibit the cytotoxic activity of NK cells to prevent cell lysis.
- Versandbedingungen:
- Ambient
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php