Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 17/TNFRSF17/BCMA (C-Fc)
Produktgrößen
10 µg
£493,00
32-9026-10UG
50 µg
£656,00
32-9026-50UG
Über dieses Produkt
- SKU:
- 32-9026
- Weitere Details:
- Source: Human Cells. MW :32.1kD. Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 17 is produced by our expression system and the target gene encoding Met1-Thr49 is expressed B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain; a 23 aa transmembrane domain; and a 113 aa intracellular domain. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF; it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF; members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface; BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development;function and regulation.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php