Recombinant Mouse Platelet glycoprotein 4/CD36 (C-Fc)
Produktgrößen
10 µg
£554,00
32-9007-10UG
50 µg
£847,00
32-9007-50UG
Über dieses Produkt
- SKU:
- 32-9007
- Weitere Details:
- Source: Human Cells. MW :73.5kD. Recombinant Mouse Platelet Glycoprotein 4 is produced by our Mammalian expression system and the target gene encoding Gly30Lys439 is expressed with a Fc tag at the C-terminus. Platelet Glycoprotein 4(CD36) is belongs to the class B scavenger receptor family. The molecule CD36 is synthesized as a 472 amino acid (aa) protein that contains a 6 aa N-terminal cytoplasmic domain; a 22 aa N-terminal transmembrane segment; a 420 aa extracellular “loopâ€; a 22 aa C-terminal transmembrane segment; and a 9 aa C-terminal cytoplasmic tail. Both cytoplasmic tails are palmitoylated; with the C-terminal tail involved in oxidized LDL binding. With respect to the extracellular loop; the N-terminal region is believed to bind both thrombospondin-1 and Plasmodium-infected erythrocytes. Other ligands for CD36 include long-chain fatty acids; collagen; phospholipids and apoptotic cells. Cells known to express CD36 include capillary endothelium; adipocytes; skeletal muscle cells; intestinal epithelium; smooth muscle cells and hematopoietic cells such as RBC’s; platelets and monocytes. On the surface of cells; CD36 is suggested to exist as a dimer in response to ligation (7). CD36 is reported to regulate fatty uptake; act as an angiogenic with TSP-1; and participate in the clearance of apoptotic phagocytes.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php