Recombinant Mouse Thrombomodulin/BDCA-3/CD141 (C-6His)
Produktgrößen
10 µg
£604,00
32-8989-10UG
50 µg
£897,00
32-8989-50UG
Über dieses Produkt
- SKU:
- 32-8989
- Weitere Details:
- Source: Human Cells. MW :54.6kD. Recombinant Mouse Thrombomodulin is produced by our Mammalian expression system and the target gene encoding Leu17-Ser517 is expressed with a 6His tag at the C-terminus. Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3); which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin; EGF-like; transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells; THBD inhibits coagulation and fibrinolysis. It functions as a cell surface receptor and an essential cofactor for active thrombin; which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI); also known as carboxypeptidase B2 (CPB2). In addition; THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis; stroke; arteriosclerosis; and cancer.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php