Recombinant Mouse Myeloperoxidase/MPO (C-10His)
Produktgrößen
10 µg
£508,00
32-8968-10UG
50 µg
£722,00
32-8968-50UG
Über dieses Produkt
- SKU:
- 32-8968
- Weitere Details:
- Source: Human Cells. MW :81.1kD. Recombinant Mouse Myeloperoxidase is produced by our Mammalian expression system and the target gene encoding Met16-Thr718 is expressed with a 10His tag at the C-terminus. Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride; bromide; and iodide to multiple reactive species. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. Modification of ApoB100; as well as the lipid and cholesterol components of LDL and HDL; promotes the development of atherosclerosis. MPO is also associated with a variety of other diseases; and inhibits vasodilation in inflammation by depleting the levels of NO. Serum albumin functions as a carrier protein during MPO movement to the basolateral side of epithelial cells. MPO is stored in neutrophil azurophilic granules. Upon cellular activation; it is deposited into pathogencontaining phagosomes. While mice lacking MPO are impaired in clearing select microbial infections;MPO deficiency in humans does not necessarily result in heightened susceptibility to infections.
- Aufreinigung:
- Purity is >95%. Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:32-8968.jpg