Recombinant Human Interleukin-13 Receptor Subunit Alpha-1/IL-13RA1(C-6His)
Produktgrößen
10 µg
£453,00
32-8917-10UG
50 µg
£508,00
32-8917-50UG
Über dieses Produkt
- SKU:
- 32-8917
- Weitere Details:
- Source: Human cells. MW :37.7kD. Recombinant Human Interleukin-13 Receptor Subunit Alpha-1 is produced by our Mammalian expression system and the target gene encoding Gly22-Thr343 is expressed with a 6His tag at the C-terminus. Interleukin-13 receptor subunit alpha-1(IL13RA1) is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha; a subunit shared by IL13 and IL4 receptors. The human IL13-Ra1 was originally cloned based on sequence homology to the mouse IL13-Ra1; it share 76% aa sequence identity. Human The IL13-Ra1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide; a 324 aa residue extracellular domain; a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. The extracellular domain of IL13-Ra1 is also closely related to that of IL13-Ra2. It binds with low affinity to interleukin-13(IL13). IL13RA1 serves as a primary IL13- binding subunit of the IL13 receptor; and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2; and thus may mediate the signaling processes that lead to the activation of JAK1; STAT3 and STAT6 induced by IL13 and IL4.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php