Recombinant Mouse Interleukin-23/IL-23
Produktgrößen
10 µg
£584,00
32-8916-10UG
50 µg
£948,00
32-8916-50UG
Über dieses Produkt
- SKU:
- 32-8916
- Weitere Details:
- Source: Human Cells. MW :19.7&35.8kD. Recombinant Mouse Interleukin-23 is produced by our Mammalian expression system and the target gene encoding Val22-Ala196&Met23-Ser335 is expressed. Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits; a p19 subunit that is unique to IL-23; and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12; as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages; dendritic cells; T cells; and endothelial cells; only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to; but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells; the effects of IL-23 is restricted to memory T cells.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php