Recombinant Mouse Fc gamma RIIIA/FCGR3/CD16 (C-6His)
Produktgrößen
10 µg
£499,00
32-8914-10UG
50 µg
£656,00
32-8914-50UG
Über dieses Produkt
- SKU:
- 32-8914
- Weitere Details:
- Source: Human cells. MW :22kD. Recombinant Mouse Low affinity IgG Fc receptor III is produced by our Mammalian expression system and the target gene encoding Ala31-Thr215 is expressed with a 6His tag at the C-terminus. Low affinity immunoglobulin gamma Fc region receptor III (Fc gamma RIII/CD16) is a member of the Ig superfamily. Based on close relationships in their extracellular domains; the Fc gamma Rs have been divided into three classes composing of Fc gamma RI (CD64); Fc gamma RII (CD32); and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Mouse CD16 is a type I transmembrane protein having two extracellular Ig-like domains consisting of immunoglobulin domain; repeat; signa and transmembrane; transmembrane helix. It is expressed on a variety of myeloid and lymphoid cells and associates with Fc R gamma to deliver an activating signal upon ligand binding. Fcgr3 is IgG binding and activation or inhibition of immune responses such as antibody-dependent cellular cytotoxicity; phagocytosis; cell surface receptor signaling pathway and positive regulation of type I/IIa/III hypersensitivity.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php