Recombinant Human Hypoxia up-Regulated Protein 1/HYOU1 (C-10His)
Produktgrößen
10 µg
£508,00
32-8903-10UG
50 µg
£722,00
32-8903-50UG
Über dieses Produkt
- SKU:
- 32-8903
- Weitere Details:
- Source: Human cells. MW :36kD. Recombinant Human Hypoxia up-Regulated Protein 1 is produced by our Mammalian expression system and the target gene encoding Met695-Leu999 is expressed with a 10His tag at the C-terminus. Hypoxia up-regulated protein 1(HYOU1) is a member of the heat shock protein 70 family. Seven members from four different heat shock protein (HSP) families were identified including HYOU1; HSPC1(HSP86); HSPA5(Bip); HSPD1(HSP60); and several isoforms of the two testis-specific HSP70 chaperones HSPA2 and HSPA1L. HYOU1 is highly expressed in many tissues; such as liver; pancreas; macrophages within aortic atherosclerotic plaques; and in breast cancers. HYOU1 has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. It may play a role as a molecular chaperone and participate in protein folding. Suppression of HYOU1 is associated with accelerated apoptosis. It is suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors; especially in breast tumors; and thus it is associated with tumor in vasiveness.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php