Recombinant Human/Mouse/Rat Irisin/FNDC5 (C-Fc)
Produktgrößen
10 µg
£558,00
32-8703-10UG
50 µg
£772,00
32-8703-50UG
Über dieses Produkt
- SKU:
- 32-8703
- Weitere Details:
- Source: Human Cells. MW :39.7kD. Recombinant Human/Mouse/Rat Irisin is produced by our Mammalian expression system and the target gene encoding Asp32-Glu143 is expressed with a Fc tag at the C-terminus. FNDC5 is a membrane protein comprised by a short cytoplasmic domain; a transmembrane segment; and an ectodomain consisting of a fibronectin type III (FNIII) domain. The ectodomain has been proposed to be cleaved to a soluble peptide hormone named “irisinâ€. Irisin is secreted from muscle in response to exercise; and may regulate energy metabolism; stem cell differentiation; and neuronal development. The circulating irisin converts white fat into the more thermogenic beige fat; and may mediate some beneficial effects of exercise in humans and the potential for generating weight loss. In mice; expression of Irisin has been shown to regulate obesity and diabetes. A similar function is suggested in human.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php