Recombinant Mouse NGAL/Lipocalin-2/LCN2 (C-Fc)
Produktgrößen
10 µg
£528,00
32-8685-10UG
50 µg
£634,00
32-8685-50UG
Über dieses Produkt
- SKU:
- 32-8685
- Weitere Details:
- Source: Human Cells. MW :48kD. Recombinant Mouse NGAL is produced by our Mammalian expression system and the target gene encoding Gln21-Asn200 is expressed with a Fc tag at the C-terminus. Lipocalin-2; also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL); is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members; Lipocalin-2 is involved in diverse cellular processes; including the transport of small hydrophobic molecules; protection of MMP-9 from proteolytic degradation; and cell signaling. Furthermore; Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor; possibly serving as a potent bacteriostatic agent by sequestering iron; regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney; prostate; and epithelia of the respiratory and alimentary tracts.Recent evidence also suggests its role as a biomarker for renal injury and inflammation.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php