Recombinant Mouse IL-1 Receptor-Like 1/IL-1RL1/IL-1 R4 (C-6His)
Produktgrößen
10 µg
£499,00
32-8657-10UG
50 µg
£656,00
32-8657-50UG
Über dieses Produkt
- SKU:
- 32-8657
- Weitere Details:
- Source: Human Cells. MW :36.6kD. Recombinant Mouse Interleukin-1 receptor-like 1 is produced by our Mammalian expression system and the target gene encoding Ser27-Ala337 is expressed with a 6His tag at the C-terminus. ST2; also called IL-1 R4; is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells; activated Th2 cells; macrophages; and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor a chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33; enhances inflammatory cytokines by activating nuclear factor-kB (NF-kB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process; while sST2 can suppress IL-33 activity.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php