Recombinant Mouse Tyrosine-Protein Kinase Receptor TYRO3/DTK (C-Fc)
Produktgrößen
10 µg
£433,00
32-8636-10UG
50 µg
£493,00
32-8636-50UG
Über dieses Produkt
- SKU:
- 32-8636
- Weitere Details:
- Source: Human Cells. MW :68.9kD. Recombinant Mouse Tyrosine Protein Kinase Receptor TYRO3 is produced by our Mammalian expression system and the target gene encoding Ala31-Ser418 is expressed with a Fc tag at the C-terminus. Dtk; also called Tyro3; belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3; Axl; and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterized for their roles in immune regulation; fertility; thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation; migration; or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues; including the central nervous; reproductive; immune; and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php