Recombinant Human Hemoglobin Subunit a/HBA1 (N-6His)
Produktgrößen
10 µg
£563,00
32-8597-10UG
50 µg
£871,00
32-8597-50UG
Über dieses Produkt
- SKU:
- 32-8597
- Weitere Details:
- Source: E.coli. MW :16.7kD. Recombinant Human Hemoglobin subunit alpha is produced by our E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the N-terminus. Hemoglobin subunit alpha 1 (HBA1); also known as a2 beta2; is a hetero-tetramer consisting of two a and two beta subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the Fe2+ state. Cooperativity of Hemoglobin (Hb) in binding with O2 and allosteric regulatory binding properties with CO2; H+; Cl-; and 2;3-DPG (2;3-bisphosphoglycerate) are based on subunit interactions. HBA1 is the most common type of Hb in adult humans; which mediates the transport of oxygen and carbon dioxide in the blood. In recent years; Hb a and beta chains have been found co-expressed in alveolar cells; mesangial cells of the kidney; retinal ganglion cells; hepatocytes and neurons. Endothelial and peripheral catecholaminergic cells express exclusively the a chain; while macrophages present the beta chain only.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php