Recombinant Human beta-1;3-Glucuronyltransferase 3/B3GAT3 (C-6His)
Produktgrößen
10 µg
£558,00
32-8575-10UG
50 µg
£772,00
32-8575-50UG
Über dieses Produkt
- SKU:
- 32-8575
- Weitere Details:
- Source: E.coli. MW :30.4kD. Recombinant Human B3GAT3 is produced by our E.coli expression system and the target gene encoding Glu72-Val335 is expressed with a 6His tag at the C-terminus. Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3) is an enzyme that in humans is encoded by the B3GAT3 gene; belongs to the glycosyltransferase 43 family. B3GAT3 is involved in a number of biological processes such as catalyzing the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans; forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate; gGlycosaminoglycans biosynthesis; transfering a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1;3-Gal-beta-1;4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans.It also plays a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins ; hows strict specificity for Gal-beta-1;3-Gal-beta-1;4-Xyl; exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl; Galbeta1-4GlcNAc and Galbeta1-4Glc and stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php