Recombinant Human Transforming Growth Factor beta-3/TGFB3
Produktgrößen
10 µg
£554,00
32-8519-10UG
50 µg
£847,00
32-8519-50UG
Über dieses Produkt
- SKU:
- 32-8519
- Weitere Details:
- Source: Human Cells. MW :12.7kD. Recombinant Human/Mouse Transforming Growth Factor beta 3 is produced by our Mammalian expression system and the target gene encoding Ala301-Ser412(Tyr340Phe) is expressed. Transforming growth factor beta 3(TGFB3) is a member of a TGF - beta superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin; matrix metalloproteases; thrombospondin -1; and a subset ofintegrins. It binds with high affinity to TGF- beta RII; a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation; embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF- beta3;mammals develop a deformity known as a cleft palate.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php