Recombinant Human Plasma Kallikrein/KLKB1 (C-6His)
Produktgrößen
10 µg
£558,00
32-8497-10UG
50 µg
£772,00
32-8497-50UG
Über dieses Produkt
- SKU:
- 32-8497
- Weitere Details:
- Source: Human Cells. MW :70.2kD. Recombinant Human Plasma kallikrein is produced by our Mammalian expression system and the target gene encoding Gly20-Ala638 is expressed with a 6His tag at the C-terminus. KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates; in a reciprocal reaction; factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. It participates in the surface-dependent activation of blood coagulation; fibrinolysis; kinin generation and inflammation.Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Biomaterials:Blood Products
- Datenblatt des Herstellers:download_pdf.php