Recombinant Human Leukocyte Elastase Inhibitor/Serpin B1/SERPINB1 (C-6His)
Produktgrößen
10 µg
£408,00
32-8478-10UG
50 µg
£610,00
32-8478-50UG
Über dieses Produkt
- SKU:
- 32-8478
- Weitere Details:
- Source: Human Cells. MW :43.8kD. Recombinant Human Serpin B1/Leukocyte elastase inhibitor is produced by our Mammalian expression system and the target gene encoding Met1-Pro379 is expressed with a 6His tag at the C-terminus. SERPINB1 is a member of the serpin family and Ov-serpin subfamily. As protease inhibitors; serpins have an array of functions including regulating blood coagulation; fibrinolysis; the complement pathway; angiogenesis; inflammation; tumor suppression; extracellular matrix remodeling; and cell motility. SERPINB1 regulates the activity of the neutrophil proteases elastase; cathepsin G; proteinase-3; chymase; chymotrypsin; and kallikrein-3. Reactive bond 1 of SerpinB1 is specific for reaction with chymotrypsin-like protease such as cathepsin G; chymotrypsin or chymase. Reactive bond 2 of SerpinB1 is specific for reaction with elastase-like protease such as neutrophyl elastase; proteinase-3; pancreatic elastase or PSA. In addition; SERPINB1 also functions as a potent intracellular inhibitor of granzyme H.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:SerpinB1-Cropped.jpg