Recombinant Human Interleukin-17A/F Heterodimer/IL-17A & IL-17F (C-6His)
Produktgrößen
10 µg
£554,00
32-8440-10UG
Über dieses Produkt
- SKU:
- 32-8440
- Weitere Details:
- Source: HEK293. MW :43.2kD. Recombinant Human IL-17A &IL-17F Heterodimer is produced by our Mammalian expression system and the target gene encoding Ile20-Ala155&Arg31-Gln163 is expressed with a 6His tag at the C-terminus. The IL-17 family include IL-17A; IL-17B; IL-17C; IL-17D; IL-17E (also called IL-25); and IL-17F. The family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. All members of the IL-17 family have a similar protein structure; with four highly conserved cysteine residues critical to their 3-dimensional shape; yet they have no sequence similarity to any other known cytokines. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23; mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17; but is induced only by IL-23 in activated monocytes.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Dilute in PBS.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg
