Recombinant Mouse C-X3-C Motif Chemokine 1/CX3CL1/Fractalkine (C-6His)
Produktgrößen
10 µg
£499,00
32-8418-10UG
50 µg
£656,00
32-8418-50UG
Über dieses Produkt
- SKU:
- 32-8418
- Weitere Details:
- Source: Human Cells. MW :34.3kD. Recombinant Mouse C-X3-C motif chemokine 1 is produced by our Mammalian expression system and the target gene encoding Gln25-Arg337 is expressed with a 6His tag at the C-terminus. Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain; a mucin-like stalk; a transmembrane a helix; and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface; and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-a-converting enzyme (ADAM17/TACE) participate in this shedding. It has been suggested that ADAM10 acts in the constitutive shedding; and ADAM17 acts in response to cell activation. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php