Recombinant Human FcRn & B2M Heterodimer (C-6His)
Produktgrößen
10 µg
£508,00
32-8384-10UG
50 µg
£722,00
32-8384-50UG
Über dieses Produkt
- SKU:
- 32-8384
- Weitere Details:
- Source: Human Cells. MW :41.4kD. Recombinant Human IgG Fc fragment receptor transporter is produced by our Mammalian expression system and the target gene encoding Ala24-Leu290&Ile21-Met119 is expressed with a 6His tag at the C-terminus. FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51(alpha chain) and Beta-2-microglobulin(Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma; mediates the uptake of IgG from milk;Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin; a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php