Recombinant Human IA2/PTPRN (Gln607-Asn686 & Trp795-Leu888; N-6His)
Produktgrößen
10 µg
£604,00
32-8366-10UG
50 µg
£897,00
32-8366-50UG
Über dieses Produkt
- SKU:
- 32-8366
- Weitere Details:
- Source: E. coli. MW :22.9kD. Recombinant Human PTPRN is produced by our E.coli expression system and the target gene encoding Gln607-Asn686&Trp795-Leu888 is expressed with a 6His tag at the N-terminus. Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain; is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules; such as their biogenesis; trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity; may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera; and thus may be a potential target of autoimmunity in diabetes mellitus.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php