Recombinant Human Guanidinoacetate N-Methyltransferase/GAMT (N; C-6His)
Produktgrößen
10 µg
£550,00
32-8260-10UG
50 µg
£741,00
32-8260-50UG
Über dieses Produkt
- SKU:
- 32-8260
- Weitere Details:
- Source: E. coli. MW :29.5kD. Recombinant Human GAMT is produced by our E.coli expression system and the target gene encoding Met1-Gly236 is expressed with a 6His tag at the N-terminus; 6His tag at the C-terminus. GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine; using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency; which is an autosomal recessive disorder characterized by developmental delay/regression; mental retardation; severe disturbance of expressive and cognitive speech; intractable seizures and movement disturbances; severe depletion of creatine/phosphocreatine in the brain; and accumulation of guanidinoacetic acid in brain and body fluids.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php