Recombinant Human Endoglin/CD105 (N-Trx; 6His)
Produktgrößen
10 µg
£558,00
32-8258-10UG
50 µg
£772,00
32-8258-50UG
Über dieses Produkt
- SKU:
- 32-8258
- Weitere Details:
- Source: E. coli. MW :33.6kD. Recombinant Human Endoglin is produced by our E.coli expression system and the target gene encoding Glu26-Gln176 is expressed with a Trx; 6His tag at the N-terminus. Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium; it has been found on endothelial cells; activated macrophages; fibroblasts; and smooth muscle cells. Furthermore; Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1); which is an autosomal dominant multisystemic vascular dysplasia; characterized by recurrent epistaxis; muco-cutaneous telangiectases; gastro-intestinal hemorrhage; and pulmonary (PAVM); cerebral (CAVM) and hepatic arteriovenous malformations.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php