Recombinant Rat Interleukin-1 Alpha/ IL-1a
Produktgrößen
10 µg
£554,00
32-8190-10UG
50 µg
£847,00
32-8190-50UG
Über dieses Produkt
- SKU:
- 32-8190
- Weitere Details:
- Source: E.coli. MW :17.9kD. Recombinant Rat Interleukin-1 Alpha is produced by our E.coli expression system and the target gene encoding Ser115-Ser270 is expressed. Interleukin 1 (IL-1) is a name that designates two proteins; IL-1aand IL-1 beta; which are the products of distinct genes; but which show approximately 25% amino acid (aa) sequence identity and which recognize the same cell surface receptors. IL-1aand IL-1 beta are both synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17;000 Da. Neither precursor contains a typical hydrophobic signal peptide sequence and most of the precursor form of IL-1a remains in the cytosol of cells; although there is evidence for a membranebound form of the precursor form of IL-1a. Although IL-1 production is generally considered to be a consequence of inflammation; evidence suggests that IL-1 is also temporally upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents; infections or microbial endotoxins; a dramatic increase in the production of IL-1 by macrophages and various other cells is seen.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php