Recombinant Human Jagged-1/JAG1/CD339 (C-Fc)
Produktgrößen
10 µg
£554,00
32-7853-10UG
50 µg
£847,00
32-7853-50UG
Über dieses Produkt
- SKU:
- 32-7853
- Weitere Details:
- Source: Human Cells. MW :138.5kD. Recombinant Human jagged-1 is produced by our Mammalian expression system and the target gene encoding Gln34-Ser1046 is expressed with a Fc tag at the C-terminus. Protein jagged-1 I; also known as Jagged-1; JAGL1; HJ1; JAG1 and CD339; is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like domain. JAG1 acts as a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. JAG1 may participate in early and late stages of mammalian cardiovascular development; JAG1 inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1 are the cause of Alagille syndrome type 1; which is autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac; skeletal; and ophthalmologic manifestations.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php