Recombinant Human Parathyroid Hormone 1 Receptor/PTH1R (Gly49; C-6His)
Produktgrößen
10 µg
£504,00
32-7621-10UG
50 µg
£669,00
32-7621-50UG
Über dieses Produkt
- SKU:
- 32-7621
- Weitere Details:
- Source: Human Cells. MW :20.2kD. Recombinant Human Parathyroid hormone 1 receptor is produced by our Mammalian expression system and the target gene encoding Tyr23-Met189 is expressed with a 6His tag at the C-terminus. Parathyroid hormone 1 receptor(PTH1R) is a multi-pass membrane protein. The protein is expressed in high levels in bone and kidney and regulates calcium ionhomeostasis through activation of adenylate cyclase and phospholipase C. In bone; it is expressed on the surface of osteoblasts. When the receptor is activated through PTH binding; osteoblasts express RANKL (Receptor Activator of Nuclear Factor kB Ligand); which binds to RANK (Receptor Activator of Nuclear Factor kB) on osteoclasts. This turns on osteoclasts to ultimately increase the resorption rate.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php